- Metabolite
- HMDB0005021 (Quetiapine)
- Biospecimen
- Cerebrospinal Fluid (CSF)
- Status
- Detected and Quantified
- Data source
- Referenced
- Concentration
- 0.0809 (0.00157-0.146) uM
- Age
- Adult (>18 years old)
- Sex
- Not Specified
- Condition
- schizophrenia (CYP3A4 rs4646437)
References
- Nikisch G, Baumann P, Oneda B, Kiessling B, Weisser H, Mathe AA, Yoshitake T, Kehr J, Wiedemann G, Eap CB: Cytochrome P450 and ABCB1 genetics: association with quetiapine and norquetiapine plasma and cerebrospinal fluid concentrations and with clinical response in patients suffering from schizophrenia. A pilot study. J Psychopharmacol. 2011 Jul;25(7):896-907. doi: 10.1177/0269881110389208. Epub 2010 Dec 8. [PubMed:21148022 ]