Concentration Details

Metabolite
HMDB0002103 (27-Hydroxycholesterol)
Biospecimen
Cerebrospinal Fluid (CSF)
Status
Detected and Quantified
Data source
Referenced
Concentration
0.0045 +/- 0.001 uM
Age
Elderly (>65 years old)
Sex
Both
Condition
Mild cognitive impairment
Comments
Also known as incipient dementia or isolated memory impairment
References
    1. Leoni V, Shafaati M, Salomon A, Kivipelto M, Bjorkhem I, Wahlund LO: Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment? Neurosci Lett. 2006 Apr 10-17;397(1-2):83-7. Epub 2006 Jan 6. [PubMed:16406316 ]